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VASCage publication in high-ranking journal „Artificial Intelligence in Medicine“: deep learning for MRI brain image analysis

MRI brain image analysis is of great significance for brain disease diagnosis, progression assessment, and monitoring of neurological conditions. Segmentation is a crucial process to determine volume, boundaries and morphology of specific brain structures in medical imaging. Manual segmentation however is time-consuming, laborious, and subjective, which significantly amplifies the need for automated processes. Now VASCage researcher Nadja Gruber, Malik Galijasevic (Medical University of Innsbruck, Dept. of Neuroradiology) and co-authors present an efficient deep learning approach for the automated segmentation of brain tissue in the high-ranking journal „Artificial Intelligence in Medicine“.

VASCage at ESOC2022: Epidemiology, Manifestions and Prognosis of acute covert brain infarctions

During an ischemic stroke a patient suffers from acute neurological symptoms due to an infarct in the brain. From time to time, however, clinicians encounter small brain infarcts on magnetic resonance imaging (MRI) scan that are very recent but did not cause any clear clinical symptoms.
In her presentation at ESOC in Lyon on 5 May 2022, VASCage researcher Annemieke ter Telgte discussed the epidemiology, clinical manifestations and prognosis of such acute covert brain infarcts. Data suggest that the prevalence of acute covert brain infarcts is increased at late adulthood and in persons with cerebral small vessel disease.
VASCage patient involvement in clinical studies

PRESS RELEASE: Stroke patients play an active role in shaping the research process. ACTpatient video now online.

In Austria, about 25,000 people suffer a stroke every year. But in Austria, the people affected are usually not actively involved in the planning and implementation of clinical studies. VASCage wants to change that. In the project ACTpatient, people with stroke and their relatives actively participate in the research process from the very beginning.

ACTpatient video (c) OIS
Link to press release (in German)
Download press picture 1 ©VASCage
Download press picture 2 ©VASCage

Brain Awareness Week - VASCage interview series - Interview with Silvia Komarek, PhD Student at VASCage

It's brain awareness week, the global campaign to foster public enthusiasm and support for brain science! VASCage runs a series of interviews with some of our researchers.

-WHAT FASCINATES YOU ABOUT THE BRAIN?
Everything a person feels or does is processed through the central nervous system. Each part of the brain holds specific functions and deficits in the brain functions can mostly be localized through

Brain Awareness Week - VASCage interview series - Interview with Michael Knoflach, neurologist at VASCage and Med. Univ. Innsbruck

It's brain awareness week, the global campaign to foster public enthusiasm and support for brain science! VASCage runs a series of interviews with some of our researchers.

-WHAT FASCINATES YOU ABOUT THE BRAIN?
The brain is a very delicate and complex organ that we might never understand in its whole function. Even though a small damage can cause severe deficits, the brain plasticity and ability to reorganize

Brain Awareness Week - VASCage interview series - Interview with Annemieke ter Telgte, postdoc at VASCage

It's brain awareness week, the global campaign to foster public enthusiasm and support for brain science! VASCage runs a series of interviews with some of our researchers.

-WHAT FASCINATES YOU ABOUT THE BRAIN?
The brain is a highly complex organ, and we are only at the start of unravelling how the brain works. It fascinates me how billions of nerve cells and non-neuronal cells act together and bring forth

VASCage scientist Sophia Kiechl with publication success: underestimated vascular risk factors in young people

Epidemiological clinical studies on vascular health are an important field of activity for VASCage. In her research, early-career scientist Sophia Kiechl has successfully focussed on adolescents and has contributed to several publications. The recent paper „Diagnostic Yield of a Systematic Vascular Health Screening Approach in Adolescents at Schools“ in the Journal of Adolescent Health has attracted particular attention. Kiechl is the first author in a team of the Department of Neurology at the Medical Univ. of Innsbruck.
covid study VASCage

VASCage researchers find cardiometabolic microRNA biomarkers that may aid in COVID-19 severity and mortality prediction

The study was conducted by VASCage project leader Prof. Manuel Mayr and his team including first author and PhD student Dr. Clemens Gutmann, who studied and practiced medicine at the Medical University of Innsbruck before joining Prof. Mayr’s group at King’s College London. In collaboration with researchers from VASCage company partner TAmiRNA GmbH in Vienna they contribute with their recent findings to fight the pandemic. They have published their results in ‘Cardiovascular Research‘, the

PRESS RELEASE: Blood vessels already suffer in youth. New VASCage publication on cardiovascular risk factors in Journal JAHA

Risk factors for heart attack and stroke such as blood and liver fat levels lead to an increase in early pathological vascular wall changes in Tyrolean adolescents. This has been shown in a representative study of Tyrolean and South Tyrolean adolescents. A recent publication by the VASCage research center and the Medical University of Innsbruck concludes that preventive care would be important not only for high-risk adolescents.
patient in ExerCube

VASCage is research partner in the European ExerGetic project. The goal is to prevent falls in geriatric patients with a whole-body videogame-based training device

Fall prevention is of utmost importance not only in stroke rehabilitation. According to the World Health Organization (WHO) around 28-35% of people aged 65 years and older fall each year. Experiences of falls are considered as stressful events which can lead to drastic consequences in social interaction, daily activities, and quality of life.

VASCage science outreach: Series of high school workshops on artificial intelligence in medicine and vascular research

VASCage regularly engages in activities to promote public awareness and understanding of science, especially for high school students and their teachers. Together with the Tyrolean science outreach association ‚klasse!forschung‘ VASCage initiated a workshop series inspiring young people to develop an interest in research.

Junior researcher Nadja Gruber is mathematician and specialist for
VACAge Nature Communications paper on Corona biomarkers

VASCage Proteomics and RNA biomarker research contributes with a new publication to fight the pandemic

A ‘Nature Communications‘ paper on prognostic COVID-19 biomarkers for intensive care patients has been published.
COVID-19 poses an unprecedented challenge to health care systems globally. It is increasingly apparent that conventional prognostic scores for patients admitted to intensive care units (ICUs) are unsuitable for outcome prediction. Now VASCage project leader Manuel Mayr of King’s College London, and his team were able to make important contributions to address this clinicial need.
pulse wave velocity measurement

PRESS RELEASE:  First signs of atherosclerosis in Tyrolean Youths? Largest clinical trial on vascular health in adolescents in Austria

EVA4YOU is an observational study enrolling students and apprentices aged between 14 and 19 years to determine predictors of the early steps of the formation of atherosclerosis. Examinations are conducted at schools and companies throughout Tyrol.
Link to press release (in German)
Download press picture 1 ©VASCage/M.Knoflach
Download press picture 2 ©VASCage/M.Knoflach
Link to the trial EVA4YOU
VASCage clinical trial post-stroke osteopathy

PRESS RELEASE: clinical trial 'Post-stroke osteopathy' on bone fractures after stroke

Patients who survive the acute phase of stroke are at a higher risk of bone fractures. VASCage has issued a press release on its new clinical trial 'Post-Stroke Osteopathy'. The objective is to characterize falls and fractures and changes in the bone microstructure after  stroke.
Link to press release (in German)
Download press picture1 ©Walch
Download press picture2 ©Meier
Download press picture3 ©Degenhart

Link to the trial Post-Stroke Osteopathy

 
spermidine rich nutrion

New research results on flies, mice and humans suggests that spermidine-rich diet might protect the ageing brain

Decreased cognitive performance is a hallmark of brain ageing, but the underlying mechanisms and potential therapeutic avenues remain poorly understood. Now, new research results with VASCage contribution raise the intriguing possibility that dietary spermidine may be protective against cognitive decline in humans. The exciting new findings are published in the current issue of the journal Cell Reports.
VASCage Consortium Meeting

VASCage GmbH company partners and scientific partners got together in our first virtual consortium meeting

Around 100 participants enjoyed the exciting talks on "Vascular Health in a Digital World" by our keynote speakers Sabine Klein (ÖGK), Winfried Ness (Helm AG) and Uwe Siebert (UMIT), the discussion with our VASCAge CSO Stefan Kiechl and the presentation of 16 project highlights! The participants also used the opportunity to network and chat in our virtual coffee area.
THANKS TO ALL OUR SPEAKERS AND PARTICIPANTS!

Cardiovascular risk factor overweight: New publications shed light on height and weight trajectories from infancy to young adulthood

A major risk factor for cardiovascular disease in young adults is overweight or obesity in adolescence. VASCage project leaders Prof. Dr. Ursula Kiechl-Kohlendorfer (Director of the Department of Paediatrics II, Division of Neonatology, Medical University of Innsbruck MUI), Assoc. Prof. Dr. Michael Knoflach (Dept. of Neurology, MUI) and her co-workers have published results that are crucial for the implementation of adequate prevention measures.
Healthy nutrition VASCage

Missed the VASCage Live Webinar 'Forever Young' at  the European Researchers' Night? Watch the video!

VASCage researcher Dr. Sophia Kiechl explained how life style affects our blood vessels and discussed nutrional trends with a very active audience (in German). The video is now online. The talk was part of the European Researchers' Night 2020, an event that takes place simulatenously once a year throughout Europe and invites the public to get a taste of the everyday life of research institutions.